| 发明名称 |
Optimized Anti-CD30 Antibodies |
| 摘要 |
An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcγR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.
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| 申请公布号 |
US2012014943(A1) |
申请公布日期 |
2012.01.19 |
| 申请号 |
US201113163465 |
申请日期 |
2011.06.17 |
| 申请人 |
XENCOR, INC. |
发明人 |
LAZAR GREGORY ALAN;DESJARLAIS JOHN R.;HAMMOND PHILIP W.;CARMICHAEL DAVID F.;CHEN BAO-IU;CHU SEUNG Y.;KARKI SHER BAHADUR;KUNKEL LORI |
| 分类号 |
A61K39/395;A61P29/00;A61P31/00;A61P35/00;A61P37/00 |
主分类号 |
A61K39/395 |
| 代理机构 |
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