发明名称 |
1-PYRAZOLO[4,3-C]ISOQUINOLINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF |
摘要 |
The invention relates to a compound of formula (I), where: R1 is a phenyl group optionally substituted by one or more halogen atoms; R2 is: a hydrogen atom or a halogen atom or a cyano group; a -C(=O)Y group where Y is a hydrogen atom, or a -NH2 or -OR3 group; a -C(=S)NH2 group; a -C(=NH)NH-OH group; a -CH2OH or -CH2F group; a -CH=N-OH group; a -CH=CH2 or -C=C-R3 group; a H or H R1 group being a hydrogen or (C1-C4)alkyl group; R3 is a hydrogen atom or (C1-C4)alkyl group; and R4 is a -NH2, (C1-C4)alkyl, (C1-C4)fluoroalkyl or (C3-C7)cycloalkyl group. |
申请公布号 |
KR20120007060(A) |
申请公布日期 |
2012.01.19 |
申请号 |
KR20117027900 |
申请日期 |
2010.04.22 |
申请人 |
SANOFI |
发明人 |
DELETTRE GEORGES;DEPRETS STEPHANIE;HALLEY FRANK;SCHIO LAURENT;THOMPSON FABIENNE |
分类号 |
C07D471/04;A61K31/4745;A61P35/00 |
主分类号 |
C07D471/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|