发明名称 PURINE COMPOUNDS SELECTIVE FOR PI3K P110 DELTA, AND METHODS OF USE
摘要 The invention provides compounds having the general formula: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and n are defined herein, compositions including the compounds and method of using the compounds to treat a disease or disorder mediated by the p110 delta isoform of PI3 kinase selected from immune disorders, cancer, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
申请公布号 US2012015931(A1) 申请公布日期 2012.01.19
申请号 US201113181647 申请日期 2011.07.13
申请人 LI JUN;SAFINA BRIAN;SUTHERLIN DANIEL P.;SWEENEY ZACHARY 发明人 LI JUN;SAFINA BRIAN;SUTHERLIN DANIEL P.;SWEENEY ZACHARY
分类号 A61K31/5377;A61P3/00;A61P3/10;A61P5/00;A61P7/00;A61P9/00;A61P19/02;A61P25/00;A61P29/00;A61P31/12;A61P35/00;A61P37/02;C07D473/16 主分类号 A61K31/5377
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