SYSTÈME DE PERFUSION À SOUFFLET À PHARMACOCINÉTIQUE/PHARMACODYNAMIQUE IN VITRO POUR AUGMENTER L'EFFICACITÉ D'UNE CHIMIOTHÉRAPIE ANTICANCÉREUSE

摘要

Provided herein is a continuous cell perfusion model system that provides useful pharmacokinetic and pharmacodynamic information on the application of new drugs or combinations of various agents in vitro to human cancer cell lines. Also provided are methods of using this system to individualize cancer treatment.