2-carboxamide-7-piperazinyl-benzofuran derivatives 774

摘要

The present invention relates to compounds of formula (I), wherein R is heteroaryl or heterocyclyl, optionally substituted R is Calkyl, heterocyclyl, Calkylaryl, Calkylheteroaryl, carbocyclyl, C alkylheterocyclyl, heterocyclylheteroaryl, arylheterocyclyl, carbocyclylheteroaryl, heterocyclylaryl, optionally substituted Ris hydrogen or Calkyl, or R and R may together with the nitrogen atom, form a saturated ring system containing 4, 5 or 6 ring forming atoms, and optionally substituted R is hydrogen, halogen, methyl or methoxy to pharmaceutical composition containing said compounds and to the use of said compounds in therapy, for instance in treating cognitive disorders. The present invention further relates to new intermediates useful in the preparation thereof.