发明名称 |
Arginine Inactivation of Viruses |
摘要 |
The present invention pertains to methods of using arginine to inactivate or reduce the infectious titer of enveloped viruses potentially present in biological compositions produced by eukaryotic cells (such as a antibodies or other therapeutic proteins). In some embodiments, inactivation or reduction of viral titers by exposure to arginine is achieved in a neutral (pH˜7) or near neutral (˜pH 6 to˜pH 8) environment.
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申请公布号 |
US2012015424(A1) |
申请公布日期 |
2012.01.19 |
申请号 |
US200913130540 |
申请日期 |
2009.11.20 |
申请人 |
SELVITELLI KEITH;MCCUE JUSTIN;BIOGEN IDEC MA INC. |
发明人 |
SELVITELLI KEITH;MCCUE JUSTIN |
分类号 |
C12N7/06;C07K16/00 |
主分类号 |
C12N7/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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