PARTIALLY ACTIVE MICROFLUIDIC SYSTEM FOR 3D CELL CULTIVATION AND METHOD FOR PERFUSION THEREOF

摘要

The invention relates to a partially active microfluidic system for cell cultivation comprising a multiwell system (4) with multiple wells (17) and cavities formed therein that hold cells. Each cavity (11) is formed by at least one inlay (3) comprising an opening (1) that does not open up directly into the cavity (11), but rather into a space (17) surrounding the cavity, wherein the medium present in the surrounding space communicates with the medium contained in the cavity (11) by way of a sieve structure in the inlay. The invention is suitable in particular for 3D cell cultivation.