发明名称 PURINE COMPOUNDS SELECTIVE FOR PI3K P110 DELTA, AND METHODS OF USE
摘要 The invention provides compounds having the general formula (I): and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and n are defined herein, compositions including the compounds and method of using the compounds to treat a disease or disorder mediated by the p110 delta isoform of ?I3 kinase selected from immune disorders, cancer, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
申请公布号 CA2802808(A1) 申请公布日期 2012.01.19
申请号 CA20112802808 申请日期 2011.07.13
申请人 F. HOFFMANN-LA ROCHE AG 发明人 LI, JUN;SAFINA, BRIAN;SUTHERLIN, DANIEL P.;SWEENEY, ZACHARY
分类号 C07D473/32;A61K31/52;A61P35/00 主分类号 C07D473/32
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