发明名称 |
BIOBURDEN-REDUCING ANTIBIOTIC COMPOSITION AND METHOD OF USE |
摘要 |
An antibiotic composition is provided for use in decontaminating biological tissue, for example, graft tissues for transplantation or preparation for terminal sterilization. The antibiotic composition is a physiological solution includes a lantibiotic, such as nisin. The antibiotic solution is effective to substantially inhibit bacterial growth of at least one type of gram-positive bacteria while substantially maintaining the physiological characteristics of the tissue. The method may include contacting the tissue with the antimicrobial composition at a temperature and for a period of time effective to substantially inhibit bacterial growth of the at least one type of gram-positive bacteria while substantially maintaining the physiological characteristics of the tissue. |
申请公布号 |
EP2405742(A2) |
申请公布日期 |
2012.01.18 |
申请号 |
EP20100708868 |
申请日期 |
2010.03.11 |
申请人 |
CRYOLIFE, INC. |
发明人 |
WALSH, STEVEN;HAMBY, JOSEPH;CHINICH, CHAD |
分类号 |
A01N1/02;C12N5/00 |
主分类号 |
A01N1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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