Probe for detection of polymorphism in abl gene, and use thereof

摘要

A probe for detecting a polymorphism in the abl gene, said probe comprising at least one fluorescence-labeled oligonucleotide selected from P1 to P9 and by way of example P 1 is an oligonucleotide comprising a nucleotide sequence complementary to a nucleotide sequence of 10 to 50 consecutive nucleotides containing nucleotides 125 to 133 in SEQ ID NO:1 or 2 or a homologous sequence thereof, wherein the nucleotide corresponding to the nucleotide at position 125 is cytosine and labeled with a fluorescent dye. The invention also extends to methods of using the probes and kits containing them.