| 发明名称 |
THIAZOLOPYRIMIDINE MODULATORS AS IMMUNOSUPPRESSIVE AGENTS |
| 摘要 |
<p>The present invention relates to a compound of formula III or IV, and/or a pharmaceutical acceptable addition salt thereof and/or a stereoisomer thereof and/or a solvate thereof,
wherein R 7 , R 8 , R 9 , R 11 and R 12 are as defined in the claim 1. The present invention also relates to a method for their preparation, as well as to pharmaceutical compositions thereof. The present invention further relates to the use of said compounds as biologically active ingredients, more specifically as medicaments for the treatment of disorders and pathologic conditions such as, but not limited to, immune and auto-immune disorders, organ and cells transplant rejections.</p> |
| 申请公布号 |
EP2405973(A2) |
申请公布日期 |
2012.01.18 |
| 申请号 |
EP20100711871 |
申请日期 |
2010.03.15 |
| 申请人 |
KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D |
发明人 |
HERDEWIJN, PIET;DE JONGHE, STEVEN;GAO, LING-JIE;JANG, MI-YEON;VANDERHOYDONCK, BART;WAER, MARK JOZEF ALBERT;LIN, YUAN;HERMAN, JEAN FERDINAND;LOUAT, THIERRY ANDRE MICHEL |
| 分类号 |
A61P29/00;A61K31/519;C07D513/04 |
主分类号 |
A61P29/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
