发明名称 |
INHIBITOR OF PLASMINOGEN ACTIVATOR INHIBITOR-1 |
摘要 |
<p>The present invention relates to a novel compound having plasminogen activator inhibitor-1 (PAI-1) inhibitory activity, and a PAI-1 inhibitor comprising the compound as an active ingredient. The present invention further relates to a pharmaceutical composition that has an inhibitory action on PAI-1 activity and is useful in the prevention and treatment of various diseases whose onset is associated with PAI-1 activity. The novel compound is represented by the following general formula. Each symbol is defined as those in the specification.</p> |
申请公布号 |
EP2272822(A4) |
申请公布日期 |
2012.01.18 |
申请号 |
EP20090729173 |
申请日期 |
2009.03.31 |
申请人 |
RENASCIENCE CO., LTD. |
发明人 |
MIYATA, TOSHIO;YAMAOKA, NAGAHISA;KODAMA, HIDEHIKO;MURANO, KENJI |
分类号 |
C07C235/74;A61K31/167;A61K31/196;A61K31/245;A61K31/34;A61K31/36;A61K31/385;A61K31/40;A61K31/415;A61K31/42;A61K31/421;A61K31/4409;A61K31/47;A61P3/10;A61P7/02 |
主分类号 |
C07C235/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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