Therapeutic pro-apoptotic BH3-like molecules and methods for generating and/or selecting the same
摘要
<p>The present invention relates generally to therapeutic molecules which are useful for modulating apoptosis in a target cell or cell population. More particularly, the present invention provides therapeutic agents which inhibit pro-survival molecules and which are capable of inducing or facilitates apoptosis of a target cell or cell population such as cancer cells. Further provided are methods for generating or selecting the therapeutic molecules and pharmaceutical compositions comprising the therapeutic molecules.</p>
申请公布号
EP2407484(A2)
申请公布日期
2012.01.18
申请号
EP20110178210
申请日期
2006.06.23
申请人
THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH
发明人
COLMAN, PETER MALCOLM;HUANG, DAVID CHING SIANG;LEE, ERINNA FAITH;FAIRLIE, WALTER DOUGLAS