发明名称 Morpholinopurine derivatives
摘要 There is provided a novel compound that inhibits phosphatidylinositol 3-kinase (PI3K) and/or the mammalian target of rapamycin (mTOR) and exhibits anti-tumor activity. The present invention provides a compound represented by the following formula (1) having various substituents that inhibits PI3K and/or mTOR and exhibits anti-tumor activity: wherein R1, R2, R3, R4, Ra, Rb, Rc, and X each have the same meaning as defined in the specification.
申请公布号 US8097622(B2) 申请公布日期 2012.01.17
申请号 US20090579175 申请日期 2009.10.14
申请人 NAKAYAMA KIYOSHI;SUGITA KAZUYUKI;SETOGUCHI MASAKI;TOMINAGA YUICHI;SAITOU MASANORI;ODAGIRI TAKASHI;DAIICHI SANKYO COMPANY, LIMITED 发明人 NAKAYAMA KIYOSHI;SUGITA KAZUYUKI;SETOGUCHI MASAKI;TOMINAGA YUICHI;SAITOU MASANORI;ODAGIRI TAKASHI
分类号 A61K31/535;C07D413/14 主分类号 A61K31/535
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