| 发明名称 |
METHOD FOR PRODUCING OSELTAMIVIR PHOSPHATE |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a new high-yield and practical chemical synthetic method of oseltamivir phosphate, with which the oseltamivir phosphate is obtained from an easily available raw material compound with high optical purity. <P>SOLUTION: In the new chemical synthetic method of the oseltamivir phosphate (10), the specified compound of an optically active cyclic epoxy ester is utilized as a starting raw material, and reaction via cyclohexenyl azide and cyclic diamide-alcohol follows. <P>COPYRIGHT: (C)2012,JPO&INPIT |
| 申请公布号 |
JP2012006921(A) |
申请公布日期 |
2012.01.12 |
| 申请号 |
JP20110119193 |
申请日期 |
2011.05.27 |
| 申请人 |
KOBE UNIV;ASAHI KASEI CHEMICALS CORP |
发明人 |
HAYASHI MASAHIKO;TANAKA TAKANORI;KAWAKUBO HIROSHI |
| 分类号 |
C07C231/12;A61K31/215;A61P31/16;C07B61/00;C07C233/52;C07C247/14;C07C269/00;C07C271/24;C07D203/26 |
主分类号 |
C07C231/12 |
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