IDENTIFICATION OF MARKER IN ESOPHAGEAL CANCER, COLON CANCER, HEAD AND NECK CANCER, AND MELANOMA

摘要

PROBLEM TO BE SOLVED: To provide a method for identifying expression of markers indicative of the presence of an esophageal cancer, a squamous cell cancer, a squamous cell cancer of the head and neck, a colon cancer, and a melanoma.

SOLUTION: The method for identifying the expression of markers indicative of the presence of esophageal cancer cells in a lymph node of a patient includes determining if a first mRNA species specific to one of CEA, CK19, CK20, TACSTD1, VIL1, PVA, and CK7 is overabundant in an RNA sample prepared from the lymph node. The method further includes determining if a second mRNA species specific to CK19 is overabundant in the RNA sample prepared from the lymph node when the first mRNA species is CEA. In this case, the overabundance of the mRNA species is indicative of the presence of displaced cells of the esophagus in the lymph node.

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