| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a cell proliferation inhibitor specific to cancer cell. <P>SOLUTION: It is discovered that although suppressing expression of the RecQ1 gene, a RecQ helicase family gene, shows suppressive effects on cell proliferation in cancer cells, such effects are not observed in human TIG3 cells (a normal diploid fibroblast cell line), which are normal cells. Hence, it is discovered that siRNAs against RecQ1 gene have cancer cell-specific cell proliferation-suppressing effects that are mediated by suppression of the expression of the gene. <P>COPYRIGHT: (C)2012,JPO&INPIT |
