The present invention provides structures formed from crosslinked polynucleotides, where a subset of the polynucleotides binds to a target under physiological conditions, where the signal group detectably changes upon binding.
申请公布号
WO2011113054(A3)
申请公布日期
2012.01.12
申请号
WO2011US28380
申请日期
2011.03.14
申请人
AURASENSE LLC;MIRKIN, CHAD, A.;THAXTON, C., SHAD;GILJOHANN, DAVID, A.;CUTLER, JOSHUA, I.
发明人
MIRKIN, CHAD, A.;THAXTON, C., SHAD;GILJOHANN, DAVID, A.;CUTLER, JOSHUA, I.