发明名称 |
(2R)-1-(3-CHLORO-2-PYRAZINYL)-2-METHYLPIPERAZINE AND SALTS THEREOF |
摘要 |
The present invention relates to a process for the preparation of compounds which are therapeutically active in the central nervous system. In one aspect, the invention relates to a process for the preparation of compounds of the general formula (I): wherein HA is a pharmaceutically acceptable acid and R1-R4 are each independently selected from the group consisting of hydrogen, halogen, C1-C6-alkyl, C1-C6-alkoxy, and di-C1-C6-alkylamino-C2-C6-alkoxy. The invention also relates to the use of said compound to manufacture a medicament for the treatment of a serotonin-related disorder.
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申请公布号 |
US2012010410(A1) |
申请公布日期 |
2012.01.12 |
申请号 |
US201113234555 |
申请日期 |
2011.09.16 |
申请人 |
FLECK TOM;FLECK BRUCE;CERNERUD MAGNUS;LUNDSTROEM HELENA;LOEFSTROEM CLAES;PELCMAN MARGIT;PAPTCHIKHINE ALEXANDER;ANDERSSON EMMA;NYGREN ALF;BIOVITRUM AB, A SWEDEN CORPORATION |
发明人 |
FLECK TOM;FLECK BRUCE;CERNERUD MAGNUS;LUNDSTROEM HELENA;LOEFSTROEM CLAES;PELCMAN MARGIT;PAPTCHIKHINE ALEXANDER;ANDERSSON EMMA;NYGREN ALF |
分类号 |
C07D401/14;C07D401/12 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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