发明名称 COMPOUNDS AND METHODS FOR REGULATING INTEGRIN CD11B/CD18
摘要 A pharmaceutical formulation of a ß2 integrin agonist including an effective amount of a ß2 integrin agonist and a pharmaceutically acceptable carrier. A method of activating ß2 integrins by interacting the ß2 integrins with a ß2 integrin agonist. A method of treating a patient by administering an effective amount of a ß2 integrin agonist, and activating ß2 integrins. A method of treating inflammation by administering a ß2 integrin agonist to a patient with inflammation, activating ß2 integrins, and reducing inflammation. Methods of treating and/or preventing renal ischemia-reperfusion (l/R) injury, reducing injury in a patient due to insertion of a stent, performing an assay for the identification of small molecule modulators of ß2 integrins, detecting a disease in a patient, and improving the general wellness of a patient.
申请公布号 WO2012005800(A1) 申请公布日期 2012.01.12
申请号 WO2011US34753 申请日期 2011.05.02
申请人 ADHAERE PHARAMACEUTICALS, INC.;GUPTA, VINEET 发明人 GUPTA, VINEET
分类号 C12N5/07;C12N5/16 主分类号 C12N5/07
代理机构 代理人
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