VON WILLEBRAND FACTOR- AND FACTOR VIII-POLYMER CONJUGATES HAVING A RELEASABLE LINKAGE

摘要

A von Willebrand Factor or Factor VIII moiety-polymer conjugate having a releasable linkage. The linkage is derived from 9H-flouroene and the polymer is a water-soluble polymer, in particular polyethylene glycol (PEG). The conjugate can be used for treating a bleeding disorder.