DIRECT REPROGRAMMING OF CELLS TO CARDIAC MYOCYTE FATE
摘要
A method for promoting conversion of cells into cardiomyocytic tissue is carried out by contacting fibrotic tissue (e.g., scar tissue) with a microRNA oligonucleotide or combination of microRNA oligonucleotides. The methods lead to direct reprogramming of fibroblasts to cardiomyocytes or cardiomyoblasts.
申请公布号
WO2012006577(A2)
申请公布日期
2012.01.12
申请号
WO2011US43438
申请日期
2011.07.08
申请人
DUKE UNIVERSITY;DZAU, VICTOR, J.;MIROTSOU, MARIA;JAYAWARDENA, TILANTHI
