| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for efficiently synthesizing a lower aliphatic optically-active fluoroalcohol that has difficulty in separation from a solvent, without using a special reaction vessel. <P>SOLUTION: In this method for producing an aliphatic optically-active alcohol having a fluorine atom at α position, the optically-active alcohol is produced by reacting an aliphatic ketone having a fluorine atom at α position in water using a formate, under the presence of an asymmetric catalyst represented by general formula (1) and an acid. <P>COPYRIGHT: (C)2012,JPO&INPIT |
