| 发明名称 |
DIRECT REPROGRAMMING OF CELLS TO CARDIAC MYOCYTE FATE |
| 摘要 |
A method for promoting conversion of cells into cardiomyocytic tissue is carried out by contacting fibrotic tissue (e.g., scar tissue) with a microRNA oligonucleotide or combination of microRNA oligonucleotides. The methods lead to direct reprogramming of fibroblasts to cardiomyocytes or cardiomyoblasts.
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| 申请公布号 |
CA2804791(A1) |
申请公布日期 |
2012.01.12 |
| 申请号 |
CA20112804791 |
申请日期 |
2011.07.08 |
| 申请人 |
DUKE UNIVERSITY |
发明人 |
DZAU, VICTOR J.;MIROTSOU, MARIA;JAYAWARDENA, TILANTHI |
| 分类号 |
C12N5/10;A61L27/54;C12N5/071;C12N15/113 |
主分类号 |
C12N5/10 |
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