NEUROPROTECTIVE COMPOUNDS

摘要

The invention describes the use of (1 S ,3 R ,7S,8 S ,8a R )-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2 R ,4 R )-tetrahydro-4-hydroxy-6-oxo-2 H -pyran-2-yl]ethyl-1-naphthalenyl propanoate derivatives, optionally mono- or di-methylated at the carbon in the alpha position of propanoic acid, of formula (I), where R is CH 3 CH 2 CO-, (CH 3 ) 2 CHCO- or (CH 3 ) 3 CCO-, its hydroxy acid forms and the pharmaceutically acceptable salts of said hydroxy acids, as neuroprotective compounds potentially useful for the prevention and/or treatment of neurodegenerative diseases, or of diseases associated with an unwanted oxidation or of age-associated pathological processes, or of epilepsy, epileptic seizures or convulsions.