ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 24P4C12 PROTEINS
摘要
<p>Antibody drug conjugates (ADC's) that bind to 24P4C12 protein and variants thereof are described herein. 24P4C12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.</p>
申请公布号
EP2403524(A1)
申请公布日期
2012.01.11
申请号
EP20100756560
申请日期
2010.03.05
申请人
AGENSYS, INC.;SEATTLE GENETICS, INC.
发明人
GUDAS, JEAN;JAKOBOVITS, AYA;AN, ZILI;MORRISON, ROBERT, KENDALL;MORRISON, KAREN, JANE MEYRICK;JIA, XIAO-CHI;BENJAMIN, DENNIS;MOSER, RUTH;SENTER, PETER
