METHOD OF EVALUATING HUMAN DENDRITIC CELLS AND HUMAN CELL IMMUNOTHERAPEUTIC AGENT

摘要

Provided is a method of evaluating the antigen presentation potential of human dendritic cells, including the following steps:
(1) a step for administering ±-galactosylceramide-pulsed human dendritic cells to a non-human mammal;
(2) a step for collecting a sample containing NKT cells from the non-human mammal;
(3) a step for detecting the activation of NKT cells present in the sample. Further provided is an agent for human NKT cell immunotherapy, containing human dendritic cells that have been assessed by the method as those possessing an antigen presentation potential for NKT cells.