| 发明名称 |
Genipin derivatives and uses thereof |
| 摘要 |
Genipin derivatives and pharmaceutical compositions thereof that inhibit the activity of uncoupling protein-2 (UCP2) and are useful in treating deficient first-phase insulin secretion, non-insulin dependent diabetes mellitus, and ischemia in a mammal are disclosed. |
| 申请公布号 |
US8093288(B2) |
申请公布日期 |
2012.01.10 |
| 申请号 |
US20090622296 |
申请日期 |
2009.11.19 |
| 申请人 |
ZHANG CHEN-YU;LOWELL BRADFORD B.;PORCO, JR. JOHN A;SHEN RUICHAO;LIN CHENG T.;KRAUSS STEFAN;BETH ISRAEL DEACONESS MEDICAL CENTER;TRUSTEES OF BOSTON UNIVERSITY |
发明人 |
ZHANG CHEN-YU;LOWELL BRADFORD B.;PORCO, JR. JOHN A;SHEN RUICHAO;LIN CHENG T.;KRAUSS STEFAN |
| 分类号 |
A61K31/35;A61K31/352;A61K31/365;C07D211/90;C07D221/04;C07D309/32;C07D311/94;C07D491/04;C07D493/04;C07D493/06 |
主分类号 |
A61K31/35 |
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