发明名称 |
Heteroaryl sulfonamides and CCR2 |
摘要 |
Compounds are provided that act as potent antagonists of the CCR2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CCR2 antagonists. |
申请公布号 |
US8093247(B2) |
申请公布日期 |
2012.01.10 |
申请号 |
US20090582001 |
申请日期 |
2009.10.20 |
申请人 |
UNGASHE SOLOMON;WEI ZHENG;BASAK ARINDRAJIT;CHARVAT TREVOR T.;CHEN WEI;JIN JEFF;MOORE JIMMIE;ZENG YIBIN;PUNNA SREENIVAS;DAIRAGHI DANIEL;HANSEN DEREK;PENNELL ANDREW M. K.;WRIGHT JOHN J.;CHEMOCENTRYX, INC. |
发明人 |
UNGASHE SOLOMON;WEI ZHENG;BASAK ARINDRAJIT;CHARVAT TREVOR T.;CHEN WEI;JIN JEFF;MOORE JIMMIE;ZENG YIBIN;PUNNA SREENIVAS;DAIRAGHI DANIEL;HANSEN DEREK;PENNELL ANDREW M. K.;WRIGHT JOHN J. |
分类号 |
A61K31/50;A61K31/44 |
主分类号 |
A61K31/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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