| 发明名称 |
HOMOGENOUS PREPARATIONS OF IL-28 AND IL-29 |
| 摘要 |
Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
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| 申请公布号 |
US2012004161(A1) |
申请公布日期 |
2012.01.05 |
| 申请号 |
US201113161720 |
申请日期 |
2011.06.16 |
| 申请人 |
BRADY LOWELL J.;KLUCHER KEVIN M.;CHAN CHUNG;DONG DENNIS L.;LIU HONG Y.;SHEPPARD PAUL O.;BUKOWSKI THOMAS R.;ZYMOGENETICS, INC |
发明人 |
BRADY LOWELL J.;KLUCHER KEVIN M.;CHAN CHUNG;DONG DENNIS L.;LIU HONG Y.;SHEPPARD PAUL O.;BUKOWSKI THOMAS R. |
| 分类号 |
A61K38/16;A61K38/00;A61K38/20;A61K38/21;A61K39/29;A61K39/395;A61K39/42;A61P31/12;C07K14/54;C07K14/555 |
主分类号 |
A61K38/16 |
| 代理机构 |
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