| 摘要 |
The present invention relates to a kit for diagnosing and screening for asthma, comprising the neuropilin (NRP) gene, and to a method for screening for a therapeutic agent for asthma using the kit. More particularly, NRP1 expression increases due to a patient having asthma and to the extracts of dust mites, and the mRNA of MMP9, protein expression, enzyme activity and promoter activity are associated with a decrease in asthma by means of the inhibition of NRP1 expression, and therefore NRP1 can be valuably used as a target for the development of therapeutic agents for asthma. |
| 申请人 |
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;LEE, HYEONG KYU;AHN, KYUNG SEOP;YOON, YOOSIK;CHOI, BYOUNG WHUI;KWON, OK-KYOUNG;KIM, SEMI;KIM, HUI SEONG;OH, SEI RYANG;YUK, JI EUN;JANG, HA YOUNG |
发明人 |
LEE, HYEONG KYU;AHN, KYUNG SEOP;YOON, YOOSIK;CHOI, BYOUNG WHUI;KWON, OK-KYOUNG;KIM, SEMI;KIM, HUI SEONG;OH, SEI RYANG;YUK, JI EUN;JANG, HA YOUNG |
