发明名称 |
MODIFIED RELEASE FORMULATIONS OF MEMANTINE ORAL DOSAGE FORMS |
摘要 |
The present invention provides pharmaceutical compositions given once daily containing at least one therapeutically active ingredient selected from the group consisting of memantine and a pharmaceutically acceptable salt of memantine, and a pharmaceutically acceptable polymeric matrix carrier. The dosage forms of the invention sustain the release of the therapeutically active agent from about 4 to about 24 hours when said dosage form is exposed to aqueous solutions. following entry of said form into a use environment, wherein said dosage form has a dissolution rate of more than about 80% after passage of about 6 hours to about 12 hours following said entry into said use environment.
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申请公布号 |
US2012004318(A1) |
申请公布日期 |
2012.01.05 |
申请号 |
US201113233381 |
申请日期 |
2011.09.15 |
申请人 |
RASTOGI SUNEEL K.;RAO NIRANJAN;PERICLOU ANTONIA;ABRAMOWITZ WATTANAPORN;DEDHIYA MAHENDRA G.;MAHASHABDE SHASHANK;FOREST LABORATORIES HOLDINGS LTD. |
发明人 |
RASTOGI SUNEEL K.;RAO NIRANJAN;PERICLOU ANTONIA;ABRAMOWITZ WATTANAPORN;DEDHIYA MAHENDRA G.;MAHASHABDE SHASHANK |
分类号 |
A61K31/13;A61K9/20;A61P25/04;A61P25/28 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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