发明名称 |
SCELETIUM EXTRACT AND USES THEREOF |
摘要 |
A composition including as an active ingredient an extract of a plant of the family Mesembryanthemaceae with mesembrenol and mesembrenone as the two major alkaloids present. The invention also relates to the use of the composition as a PDE4 inhibitor and as a serotonin-uptake inhibitor, preferably applied in formulations for the use of the composition as a dual serotonin-uptake inhibitor and PDE4 inhibitor. The invention extends to compositions, such as pharmaceutical compositions or compositions used as dietary supplements, the total alkaloid content of which includes at least 80% (w/w) combined content of mesembrenol and mesembrenone, less than 5% (w/w) mesembrine, and at least 7% (w/w) mesembranol. |
申请公布号 |
US2012004275(A1) |
申请公布日期 |
2012.01.05 |
申请号 |
US201013256674 |
申请日期 |
2010.03.16 |
申请人 |
GERICKE NIGEL;HARVEY ALAN;VILJOEN ALVARO;HOFMEYR DEON;H.L. HALL & SONS LIMITED |
发明人 |
GERICKE NIGEL;HARVEY ALAN;VILJOEN ALVARO;HOFMEYR DEON |
分类号 |
A61K31/404;A61P1/04;A61P1/16;A61P3/00;A61P9/00;A61P11/06;A61P11/14;A61P17/00;A61P17/06;A61P19/02;A61P19/06;A61P25/00;A61P25/16;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P29/00;A61P31/00;A61P31/06;A61P31/10;A61P31/16;A61P35/00;A61P37/08 |
主分类号 |
A61K31/404 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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