| 发明名称 |
TREATMENT OF NUCLEAR FACTOR (ERYTHROID-DERIVED 2)-LIKE 2 (NRF2) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO NRF2 |
| 摘要 |
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Nu-clear factor (erythroid-derived 2)-like 2 (NRF2), in particular, by targeting natural antisense polynucleotides of Nuclear factor (erythroid-derived 2)-like 2 (NRF2). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of NRF2.
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| 申请公布号 |
US2012004184(A1) |
申请公布日期 |
2012.01.05 |
| 申请号 |
US201013256720 |
申请日期 |
2010.03.16 |
| 申请人 |
COLLARD JOSEPH;KHORKOVA SHERMAN OLGA;COITO CARLOS |
发明人 |
COLLARD JOSEPH;KHORKOVA SHERMAN OLGA;COITO CARLOS |
| 分类号 |
A61K31/7088;A61K31/712;A61K31/7125;A61K31/713;A61K38/02;A61P1/00;A61P1/16;A61P3/10;A61P9/10;A61P11/00;A61P11/06;A61P17/00;A61P21/00;A61P25/00;A61P27/02;A61P29/00;A61P35/00;A61P37/04;A61P37/06;C07H21/00;C07H21/02;C07H21/04;C07K2/00;C12N5/00 |
主分类号 |
A61K31/7088 |
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