摘要 |
<p>The present invention provides an improved process for preparing HMG-CoA reductase inhibitors such as rosuvastatin calcium, fluvastatin sodium, and pitavastatin calcium under a mild condition, using a novel amide-bond-containing compound having R2-N-O-R1 moiety as a key intermediate. And also, the present invention provides the novel compound, an intermediate useful for the preparation thereof, and a process for the preparation thereof.</p> |
申请人 |
YUHAN CORPORATION;JU, HYUN;JOUNG, SANG-SUN;YI, HYUN-JIK;KHOO, JA-HEOUK;LIM, JONG-CHUL;KIM, JAE-GYU |
发明人 |
JU, HYUN;JOUNG, SANG-SUN;YI, HYUN-JIK;KHOO, JA-HEOUK;LIM, JONG-CHUL;KIM, JAE-GYU |