2-PYRIDYL SUBSTITUTED IMIDAZOLES AS THERAPEUTIC ALK5 AND/OR ALK4 INHIBITORS
摘要
This invention relates to 2-pyridyl substituted imidazoles which are inhibitors of the transforming growth factor-ß (TGF-ß) type I receptor (ALK5) and/or the activin type I receptor (ALK4), methods for their preparation, and their use in medicine, specifically in the treatment and prevention of a disease state mediated by these receptors.
申请公布号
CA2803577(A1)
申请公布日期
2012.01.05
申请号
CA20112803577
申请日期
2011.06.24
申请人
EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION
发明人
KIM, DAE KEE;SHEEN, YHUN YHONG;JIN, CHENG HUA;PARK, CHUL-YONG;SREENU, DOMALAPALLY;RAO, KOTA SUDHAKAR;KRISHNAIAH, MADDEBOINA;SUBRAHMANYAM, VURA BALA
