发明名称 |
Pyrazole or triazole compounds and their use for the manufacture of a medicament for treating somatic mutation-related diseases |
摘要 |
The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA. |
申请公布号 |
EP2402323(A2) |
申请公布日期 |
2012.01.04 |
申请号 |
EP20100185139 |
申请日期 |
2005.10.13 |
申请人 |
PTC THERAPEUTICS, INC. |
发明人 |
ALMSTEAD, NEIL;KARP, GARY MITCHELL;WILDE RICHARD GERALD;WELCH, ELLEN;CAMPBELL, JEFFREY ALLEN;REN, HONGYU;CHEN, GUANGMING |
分类号 |
A61K31/4245;A61K31/433;A61P35/00;C07D277/30;C07D417/10 |
主分类号 |
A61K31/4245 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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