| 发明名称 |
Substituted alkylamine derivatives and methods of use |
| 摘要 |
<p>Describes the N-(3,3-dimetylindolin-6-yl) {2 - [(4-pyridylmethyl) amino] (3-pyridyl))-carboxamide and pharmaceutically acceptable salt thereof. The carboxamide or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition containing it is used in the manufacture of a medicament for the treatment and prophylaxis of cancer, angiogenesis mediated diseases, neoplasia and diseases associated with KDR receptors.</p> |
| 申请公布号 |
SK287860(B6) |
申请公布日期 |
2012.01.04 |
| 申请号 |
SK20030000858 |
申请日期 |
2002.01.11 |
| 申请人 |
AMGEN INC. |
发明人 |
CHEN GUOQING;ADAMS JEFFREY;BEMIS JEAN;BOOKER SHON;CAI GUOLIN;CROGHAN MICHAEL;DIPIETRO LUCIAN;DOMINGUEZ CELIA;ELBAUM DANIEL;GERMAIN JULIE;GEUNS-MEYER STEPHANIE;HANDLEY MICHAEL;HUANG QI;KIM JOSEPH L.;KIM TAE-SEONG;KISELYOV ALEXANDER;OUYANG XIAOHU;PATEL VINOD F.;SMITH LEON M.;STEC MARKIAN;TASKER ANDREW;XI NING;XU SHIMIN;YUAN CHESTER CHENGUANG |
| 分类号 |
C07D409/12;A61K31/4436;A61K31/444;A61K31/4709;A61K31/496;A61K31/501;A61K31/506;A61K31/5377;A61P9/10;A61P11/06;A61P15/08;A61P17/06;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07D213/82;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D407/14;C07D409/04;C07D409/14;C07D413/14;C07D417/14;C07D471/04 |
主分类号 |
C07D409/12 |
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