| 发明名称 |
METHODS FOR SITE-SPECIFIC PEGYLATION |
| 摘要 |
The present invention relates to methods for the chemo-selective pegylation of the cysteine residue having unoxidized sulfhydryl side-chain and free alpha-amino group in proteins, peptides and other molecules. Similar methods are provided for the chemo-selective pegylation of the homocysteine, selenocysteine, penicillamine, and N-methyl-cysteine residues. |
| 申请公布号 |
EP2021397(A4) |
申请公布日期 |
2012.01.04 |
| 申请号 |
EP20070795425 |
申请日期 |
2007.05.25 |
| 申请人 |
IPSEN PHARMA |
发明人 |
DONG, ZHENG, XIN;EYNON, JOHN, S. |
| 分类号 |
C08G63/00;C07K16/00;C08G65/00 |
主分类号 |
C08G63/00 |
| 代理机构 |
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