发明名称 |
Method for isolating hepatitis C virus peptides |
摘要 |
Described is a method for isolating Hepatitis C Virus peptides (HPs) which have a binding capacity to a MHC/HLA molecule or a complex comprising said HCV-peptide and said MHC/HLA molecule characterized by the following steps: - providing a pool of HCV-peptide, said pool containing HCV-peptides which bind to said MHC/HLA molecules and HCV-peptides which do not bind to said MHC/HLA molecule, -contacting said MHC/HLA molecule with said pool of HCV-peptides whereby a HCV-peptide which has a binding capacity to said MHC/HLA molecule binds to said MHC/HLA molecule and a complex comprising said HCV-peptide and said MHC/HLA molecule is formed, -detecting and optionally separating said complex from the HCV-peptide which do not bind to said MHC/HLA molecule and optionally isolating and characterising the HCV-peptide from said complex. |
申请公布号 |
EP2402026(A2) |
申请公布日期 |
2012.01.04 |
申请号 |
EP20110166299 |
申请日期 |
2003.08.27 |
申请人 |
INTERCELL AG |
发明人 |
BUSCHLE, MICHAEL;HABEL, ANDRE;KLADE, CHRISTOPH;MATTNER, FRANK;OTAVA, OLEKSANDR;VYTVYTSKA, ORESTA;ZAUNER, WOLFGANG;ZINKE, SANDRA;KIRLAPPOS, HELEN |
分类号 |
A61K39/12;A61K38/00;A61K38/08;A61K38/16;A61K39/00;A61K39/145;A61K39/29;A61K39/39;A61P31/00;C07K7/06;C07K7/08;C07K14/005;C07K14/045;C07K14/11;C07K14/18;G01N33/576 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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