发明名称 1,2,3,4-tetrahydroisoquinoline derivative and its use as orexin receptor antagonist
摘要 <p>The invention relates to the compound (R)-2-[(S)-1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1 H -isoquinolin-2-yl]- N -isopropyl-2-phenyl-acetamide; and to its use as active ingredient in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compound, pharmaceutical compositions containing the compound and methods of treatment comprising administration of said compound to a human being.</p>
申请公布号 EP2402322(A1) 申请公布日期 2012.01.04
申请号 EP20100006843 申请日期 2010.07.02
申请人 ACTELION PHARMACEUTICALS LTD. 发明人 BOSS, CHRISTOPH;BRISBARE-ROCH, CATHERINE;JENCK, FRANCOIS;STEINER, MICHEL
分类号 C07D217/20;A61K31/472;A61P25/00 主分类号 C07D217/20
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