发明名称 |
MEDICAL DEVICES AND METHODS FOR MODULATION OF PHYSIOLOGY USING DEVICE-BASED SURFACE CHEMISTRY |
摘要 |
<p>This invention provides implantable medical devices having at least one moiety attached to the surface capable of catalyzing a reaction in vivo. The implantable medical device has a body such as a stent with a surface adapted to be placed adjacent to a biological tissue or fluid. The body has at least one moiety attached to the surface which is capable of catalyzing a first reaction upon contacting a first substrate in the biological tissue or fluid. The moiety remains attached to the surface after the first reaction and is capable of catalyzing at least a second reaction upon contacting a second substrate. In preferred embodiments the moiety is capable of catalyzing a multitude of reactions as substrates come into contact and then leave the surface of the device.</p> |
申请公布号 |
CA2597296(C) |
申请公布日期 |
2012.01.03 |
申请号 |
CA20062597296 |
申请日期 |
2006.02.06 |
申请人 |
SAFFRAN, BRUCE N. |
发明人 |
SAFFRAN, BRUCE N. |
分类号 |
A61L31/16;A61F2/82;A61F2/90;A61L31/02;A61L31/04;A61M1/36;A61M31/00 |
主分类号 |
A61L31/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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