发明名称 HETEROARYL SUBSTITUTED PYRROLES USEFUL AS INHIBITORS OF PROTEIN KINASES
摘要 The present invention provides compounds that are inhibitors of protein kinase, particularly inhibitors of ERK2, GSK3, PKA, CDK2 protein kinases, mammalian protein kinases involved in proliferative and neurodegenerative disorders. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of utilizing those compositions in the treatment of various disorders.
申请公布号 CA2515132(C) 申请公布日期 2012.01.03
申请号 CA20042515132 申请日期 2004.02.03
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 ARONOV, ALEX;HALE, MICHAEL R.;MALTAIS, FRANCOIS;TANG, QING
分类号 C07D403/04;A61K31/4025;A61P35/00;C07D401/14;C07D487/04;C08K5/34;C08K5/48 主分类号 C07D403/04
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