发明名称 |
METHODS AND COMPOSITIONS FOR RNA INTERFERENCE |
摘要 |
<p>The present invention provides methods for attenuating gene expression in a cell using gene-targeted double stranded RNA (dsRNA). The dsRNA contains a nucleotide sequence that hybridizes under physiologic conditions of the cell to the nucleotide sequence of at least a portion of the gene to be inhibited (the "target" gene).</p> |
申请公布号 |
SI1546174(T1) |
申请公布日期 |
2011.12.30 |
申请号 |
SI20030032042T |
申请日期 |
2003.01.22 |
申请人 |
COLD SPRING HARBOR LABORATORY |
发明人 |
BERNSTEIN EMILY;CAUDY AMY;HANNON GREGORY J.;PADDISON PATRICK J.;CONKLIN DOUGLAS;SCOTT HAMMOND |
分类号 |
C12N15/113;G01N33/50;A01K67/027;A61K31/7105;A61K38/00;A61K48/00;A61P31/18;C12N5/10;C12N15/09;C12N15/10;C12N15/11;C12Q1/02;C12Q1/68;G01N33/15 |
主分类号 |
C12N15/113 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|