| 摘要 |
METHODS FOR TREATING DISEASED OR DAMAGED TISSUE IN A SUBJECT ARE DISCLOSED, INVOLVING ADMINISTERING TO SAID SUBJECT AT A SITE WHEREIN DISEASED OR DAMAGED TISSUE OCCURS, CELLS OF A TYPE(S) NORMALLY FOUND IN HEALTHY TISSUE CORRESPONDING TO THE DISEASED OR DAMAGED TISSUE, AND/OR SUITABLE PROGENITOR CELLS THEREOF, IN ASSOCIATION WITH BIORESORBABLE BEADS OR PARTICLES AND OPTIONALLY A GEL AND/OR GEL-FORMING SUBSTANCE. WHERE THE CELLS AND/OR SUITABLE PROGENITOR CELLS THEREOF ARE CHONDROCYTES, EMBRYONIC STEM CELLS AND/OR BONE MARROW STROMAL CELLS, THE METHODS OF THE INVENTION ARE SUITABLE FOR TREATING, FOR EXAMPLE, ARTICULAR CARTILAGE DEGENERATION ASSOCIATED WITH PRIMARY OSTEOARTHRITIS. ALSO DISCLOSED IS A DEVICE HAVING TISSUE-LIKE CHARACTERISTICS FOR TREATING DISEASED OR DAMAGED TISSUE IN A SUBJECT, WHEREIN THE DEVICE COMPRISES CELLS OF A TYPE(S) NORMALLY FOUND IN HEALTHY TISSUE CORRESPONDING TO THE DISEASED OR DAMAGED TISSUE, AND/OR SUITABLE PROGENITOR CELLS THEREOF, IN ASSOCIATION WITH BIORESORBABLE BEADS OR PARTICLES AND OPTIONALLY A GEL AND/OR GE-FORMING SUBSTANCE.
|
