发明名称 PYRIDINE METHYLENE AZOLIDINONES AND THEIR USE AS PHOSPHOINOSITIDE INHIBITORS
摘要 <p>The present invention relates to pyridine methylene azolidinone compounds of Formula (I) for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, allergy, asthma, pancreatitis, multi-organ failure, kidney diseases, platelet aggregation, cancer, sperm motility, graft rejection or lung injuries. Specifically, the present invention is related to pyridine methylene azolidinone derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide-3-kinases, PI3Ks.</p>
申请公布号 SI1786812(T1) 申请公布日期 2011.12.30
申请号 SI20050031418T 申请日期 2005.09.02
申请人 MERCK SERONO SA 发明人 RUECKLE THOMAS;QUATTROPANI ANNA;POMEL VINCENT;DORBAIS JEROME;COVINI DAVID;BISCHOFF ALEXANDER
分类号 A61K31/4353;A61K31/519 主分类号 A61K31/4353
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