ENANTIOMERICALLY PURE AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS.

摘要

ENANTIOMERICALLY PURE COMPOUND OF FORMULA 1 ARE PROVIDED, AS WELL AS METHODS FOR THEIR SYNTHESIS AND USE. PREFERRED COMPOUNDS ARE POTENT INHIBITORS OF THE C-MET PROTEIN KINASE, AND ARE USEFUL IN THE TREATMENT OF ABNORMAL CELL GROWTH DISORDERS, SUCH AS CANCERS.