NOVEL CRYSTAL FORMS OF TRICYCLIC BENZOPYRAN COMPOUND AND PROCESSES FOR PRODUCING SAME

摘要

To provide crystal forms of (3R, 4S)-7-hydroxymethy1-2,2,9-trimethy1-4-(phenethylamino)-3,4-dihydro-2H-pyrano[2,3-dquinolin-3-ol that are excellent as a drug, and production methods thereof. [MEANS FOR SOLVING THE PROBLEMS]Production methods including crystallizing (3R, 4S)-7-hydroxymethy1-2,2,9-trimethy1-4-(phenethylamino)-3,4-dihydro-2H-pyrano[2,3-giquinolin-3-ol from an acetate ester solvent, an aliphatic hydrocarbon solvent, a nitrile solvent, an aromatic hydrocarbon solvent, a ketone solvent or an ether solvent, and crystal forms obtained according to the methods.Figure 1[err]