发明名称 |
MOLECULES AND METHODS OF USING SAME FOR TREATING ErbB/ErbB LIGANDS ASSOCIATED DISEASES |
摘要 |
A method of selecting a target for treatment of a hyperproliferative disease in a subject in need thereof is disclosed. The method comprising analyzing an amount and/or activity of at least one ErbB ligand in a biological sample from the subject, wherein an ErbB ligand which shows an up-regulated amount and/or activity compared to a non-hyperproliferative cell or tissue above a predetermined level is selected as a target for treatment of the hyperproliferative disease. Methods of treating hyperproliferative diseases, monoclonal antibodies and pharmaceutical compositions are also disclosed. |
申请公布号 |
WO2011132182(A9) |
申请公布日期 |
2011.12.29 |
申请号 |
WO2011IL00269 |
申请日期 |
2011.03.22 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD.;LINDZEN, MOSHIT;YARDEN, YOSEF |
发明人 |
LINDZEN, MOSHIT;YARDEN, YOSEF |
分类号 |
G01N33/50;G01N33/574 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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