RADIATION SENSITIZING COMPOSITION FOR CANCER THERAPHY COMPRISING FTS EXPRESSION INHIBITING AGENT AS ACTIVE INGREDIENT AND COMPOSITION FOR PROTECTING CELL FROM RADIATION COMPRISING FTS PROTEIN OR ITS EXPRESSION CONSTRUCT AS ACTIVE INGREDIENT

摘要

PURPOSE: A composition containing FTS expression inhibitor for cancer cell radiation sensitizing is provided to induce cancer cell apoptosis and to improve radiation sensitivity of cancer cells. CONSTITUTION: A composition for cancer cell radiation sensitizing contains FTS expression inhibitor as an active ingredient. The inhibitor is siRNA or shRNA for a nucleotide sequence encoding FTS. The nucleotide sequence encoding FTS contains a sequence of sequence number 2 or 3. The shRNA contains a sequence of sequence number 4, 5, or 6. The composition contains pharmaceutically effective amount of the inhibitor and a pharmaceutically acceptable carrier. A composition for cell protection from radiation contains FTS protein or an expression construct of the nucleotide encoding FTS protein as an active ingredient.